Cervical cancer is the second most common cancer among women, second only to breast cancer. There are about 150,000 new cases of cervical cancer in China every year, and about 100,000 people die of cervical cancer every year. On average, one woman dies of cervical cancer every 6 minutes.
The 5-year survival rate of early treatment for cervical cancer is 100% and that of late treatment is only 20%-50%. Therefore, early diagnosis and treatment are the key to prevent and treat cervical cancer.
The International Association for Cancer Research (IARC) believes that human papillomavirus (HPV) infection is the main cause of cervical cancer. Clinical studies worldwide have shown that 99.7% of cervical cancer tissue specimens can detect the presence of HPV DNA. Early detection, the cure rate of cervical cancer will reach 100%.
HPV belongs to the family Papillomaviridae and the genus Papillomavirus. It has tissue specificity, proliferates only in skin and mucosa, and does not produce viremia. At present, more than 100 types of HPV have been found, of which more than 30 are related to reproductive tract infection
HPV viruses are classified into high-risk and low-risk types according to their pathogenic risk.
High-risk type: It is mainly associated with cervical cancer and precancerous lesions. It has been proved that 99.7% of cervical cancer patients can detect high-risk HPV infection.
Low-risk type: It mainly leads to genital condyloma acuminatum, affecting the quality of life. Scientific research shows that a considerable proportion of low-risk HPV infections are accompanied by high-risk mixed infections. Therefore, it is more important to detect high-risk HPV virus in clinical patients with condyloma acuminatum.
The main culprit of cervical cancer is persistent infection of high-risk HPV virus
After the normal cervical high-risk HPV persistent infection, the cytopathic changes may develop towards the precancerous stage of cervical epithelial cell neoplasia, which will eventually lead to cervical cancer. The development of precancerous stage to cervical cancer requires 9-25 years of early detection, early detection of HPV infection and timely treatment, which can block the development of cancer.
Scientific research has shown that preventing persistent infection of high-risk HPV prevents cervical cancer.